I am a huge science fiction fan with a special spot in my heart for monster movies... I love old fashioned horror but am not as well versed in the current market...hats of to Vincent Price and all B movie classics!
I love to read scripts as well as write so if you need a second set of eyes, let me know!
Write what you enjoy. "Pretty Woman" started off as "3,000". Read both, and let me know if you could see that being a natural mesh between the two tones. If you are going to write it, it really should be fun for you, first. Best wishes on writing it.
500 Days of Summer and The F Word are great. If those fall in that category then the genre isn't dead. It just needs different angles and not the exact same structure as a Matt M. Movie